S. L. Khankin “Clinical and endoscopic assessment of the occurrence and development of epithelial neoplasms of the colon” (abstract of doctoral dissertation, 1992)
Despite the implementation of programs for mass examinations and prevention of colon cancer in most industrialized countries, so far there has been no significant decrease in the frequency of this disease. Statistical data, on the contrary, indicate that the upward trend in the incidence and mortality rates of patients with colon cancer continues (E.S. Simkina, 1979; V.D. Fedorov, 1984; D.G. Zaridze et al., 1988; R.G. Ziegler et. al., 1986). In this regard, there is reason to believe that the risk groups identified within these programs do not fully correspond to the structure of the incidence of colon cancer due to the lack of sufficiently accurate information about the peculiarities of the occurrence and development of epithelial tumors.